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α-mycolic acid  (Avanti Polar)


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    Avanti Polar α-mycolic acid
    α Mycolic Acid, supplied by Avanti Polar, used in various techniques. Bioz Stars score: 93/100, based on 10 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/α-mycolic acid/product/Avanti Polar
    Average 93 stars, based on 10 article reviews
    α-mycolic acid - by Bioz Stars, 2026-02
    93/100 stars

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    Figure 5. Mycolic acid-treated Tollip−/− macrophages accumulate lipids and permit increased Mtb replication A-B) LipidTox neutral lipid stain MFI in alveolar macrophages (AM; p=0.03), monocyte- derived macrophages (MDM), and neutrophils (PMN) from mixed bone marrow chimeric mice 28 days after Mtb infection (dpi). B) Representative histogram of AM and MDM lipid staining (B6 – blue; Tollip−/− – red). Lines connect B6 and Tollip−/− AM from the same mouse. * p < 0.05, paired two-sided t-test; N = 5. Experiment was performed five times.

    Journal: Nature microbiology

    Article Title: TOLLIP inhibits lipid accumulation and the integrated stress response in alveolar macrophages to control Mycobacterium tuberculosis infection.

    doi: 10.1038/s41564-024-01641-w

    Figure Lengend Snippet: Figure 5. Mycolic acid-treated Tollip−/− macrophages accumulate lipids and permit increased Mtb replication A-B) LipidTox neutral lipid stain MFI in alveolar macrophages (AM; p=0.03), monocyte- derived macrophages (MDM), and neutrophils (PMN) from mixed bone marrow chimeric mice 28 days after Mtb infection (dpi). B) Representative histogram of AM and MDM lipid staining (B6 – blue; Tollip−/− – red). Lines connect B6 and Tollip−/− AM from the same mouse. * p < 0.05, paired two-sided t-test; N = 5. Experiment was performed five times.

    Article Snippet: Mycolic acid preparation Synthetic α-mycolic acid (C80) in a mixture of three isoforms (alpha, keto, hydroxy) in equal measure was obtained from Avanti Polar Lipids.

    Techniques: Staining, Derivative Assay, Infection